Download Rökan: Ginkgo biloba / Recent Results in Pharmacology and by E. W. Fünfgeld (auth.), E. W. Fünfgeld (eds.) PDF

By E. W. Fünfgeld (auth.), E. W. Fünfgeld (eds.)

In this compendium the scientific and pharmacological houses of Ginkgo biloba, a standardized drug and the topic of accelerating world wide curiosity, are heavily portrayed. result of reviews are provided the following which illustrate the effect of Ginkgo on haemodynamic and rheologic parameters, metabolism and neurotransmitters. as well as papers reporting on experimental study, info also are provided which offer enterprise interdisciplinary facts for its winning healing software, peculiarly within the following indication components: cerebral insufficiency with accompanying indicators of dizziness, tinnitus, headache and reminiscence loss, lability of temper and concerned states, and peripheral arterial disease.

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Additional info for Rökan: Ginkgo biloba / Recent Results in Pharmacology and Clinic

Example text

The leaves are harvestedfrom trees growing in plantations in South Korea, Japan, and France. The mode of culture, harvesting, and extraction are perfectly standardized and controlled. Analysis of Ginkgo bi/oba extract makes it possible to confirm that undesirable substances have been eliminated and to measure the amount of active principles. The extract contains flavonoid substances, such as the Ginkgojlavone glycosides and terponoids which are characteristic of Ginkgo and have a unique structure (ginkgolides, bilobalide).

This property is well demonstrated by radiobiology: living organisms are much more altered by Y, X, and particulate radiations administered in an oxygen atmosphere than in presence of an inert gas such as nitrogen or argon. The free radicals appearing through rupture of covalent bonds easily recombine in inert atmosphere, whereas the peroxides formed with oxygen are the origing of successions of radical reactions. Lipid autoxidation Polyunsaturated fatty acids are capital elements in cellular architecture.

P. R. Eck, J. McCabe, S. Skinner would modify the metabolic situation, and, in the case of OFT, the erythrocytes and the liver would be the compartments limiting the excretion rate. 5 hours, although a second maximum might perhaps be discerned at 12 hours. However, the large dose ofEGb (380 mglkg) can slow gastrointestinal transit and disturb absorption, which may be corroborated by the absence of feces during the first 12 hours(5). The rapid appearance of radioactivity in the blood following oral administration of EGb suggests that the gastric mucosa and, to a lesser degree, the jejunum and ileum are the absorption sites, without taking into consideration the existence of an enterohepatic cycle, which has not been identified.

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