Download Pharmacology & Therapeutics of Constitutively Active by Ya-Xiong Tao PDF

By Ya-Xiong Tao

Volume 70 of Advances in Pharmacology provides the pharmacology and therapeutics of constitutively energetic receptors. With a number of chapters and the easiest authors within the box, the quantity is a necessary source for pharmacologists, immunologists, and biochemists alike.

Advances in Pharmacology presents a wealthy number of studies on well timed subject matters. The sequence areas emphasis at the molecular bases of drug motion, either utilized and experimental.

  • Contributions from the simplest authors within the field
  • An crucial source for pharmacologists, immunologists, and biochemists

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1984). Location and function of voltagesensitive conductances in retinal rods of the salamander, Ambystoma tigrinum. Journal of Physiology, 354, 203–223. 28 Paul Shin-Hyun Park Baylor, D. , Nunn, B. , & Schnapf, J. L. (1984). The photocurrent, noise and spectral sensitivity of rods of the monkey Macaca fascicularis. Journal of Physiology, 357, 575–607. Becker, R. , & Freedman, K. (1985). A comprehensive investigation of the mechanism and photophysics of isomerization of a protonated and unprotonated Schiff-base of 11-cis-retinal.

L. (2003). Assessing structural elements that influence Schiff base stability: Mutants E113Q and D190N destabilize rhodopsin through different mechanisms. Vision Research, 43, 2991–3002. Janz, J. , Fay, J. , & Farrens, D. L. (2003). Stability of dark state rhodopsin is mediated by a conserved ion pair in intradiscal loop E-2. The Journal of Biological Chemistry, 278, 16982–16991. , Cornwall, M. , & Oprian, D. D. (2003). Opsin activation as a cause of congenital night blindness. Nature Neuroscience, 6, 731–735.

Brann, M. R. (1997). Constitutive activation of the M5 muscarinic receptor by a series of mutations at the extracellular end of transmembrane 6. Biochemistry, 36, 10109–10116. , Edwards, P. , Oprian, D. , et al. (2011). The structural basis of agonist-induced activation in constitutively active rhodopsin. Nature, 471, 656–660. , & Hwa, J. (2002). Rhodopsin and retinitis pigmentosa: Shedding light on structure and function. Receptors & Channels, 8, 33–50. Stryer, L. (1991). Visual excitation and recovery.

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