By M. J. Groves
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Additional info for Parenteral Products. The Preparation and Quality Control of Products for Injection
Journal of the American Pharmaceutical Association, 47 (2), 101. Windheuser, J. , Best, M. L. and Perrin, J. H. (1970). Evaluation of sustained action parenteral emulsions. Bulletin of the Parenteral Drug Association, 24(6), 286. Wing, W. T. (1960). An examination of the decomposition of dextrose solution during sterilisation. Journal of Pharmacy and Pharmacology, 12, 19 IT. Wretlind, A. (1964), The pharmacological basis for the use of fat emulsions in intravenous nutrition, >1 CÍA Chirurgiealis Scandinavia, Suppl.
Fancher, J. , Schurr, P. Ε. and Webster, H. D. (1957). Composition, preparation and testing of an intravenous fat emulsion, Metabolism, 6, 591. Nash, R. A. (1965). Formulation of pharmaceutical suspensions, I, Drug and Cosmetic Industry, 97, 843. Nash, R. A. (1966). , 98, 39. Nash, R. A. (1972). Parenteral suspensions, Bulletin of the Parenteral Drug Association, 26 (2), 91. Platcow, E. L. and Voss, Ε. (1954). A study of the adaptability of iso-propyl myristate for use as a vehicle for parenteral injections,/owrnj/ of the American Pharmaceutical Association (Scientific Edition), 43 (11), 690.
Inlet of the dissolved solid as a jet in the centre of the flowing precipitant fluid d. motor driven syringe for the addition of the solution through the jet (c). This method has an advantage over most of the others since it is possible to prepare a suspension of a drug under sterile condirions so that either the sterüe soUd can be recovered, washed free of the intermediate solvent and re-suspended, or, if the intermediate solvent is physiologically 28 The Formulation of Parenteral Products acceptable, the suspension can be used as it is prepared.