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By Harvey B. Sarnat MD FRCPC, Paolo Curatolo

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Additional resources for Malformations of the Nervous System: Handbook of Clinical Neurology Vol 87 (Series Editors: Aminoff, Boller and Swaab)

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Siebert JR, Astley SJ, Clarren SK (1991). Holoprosencephaly in a fetal macaque (Macaca nemestrina) following weekly exposure to ethanol. Teratology 44: 29–36. Simon EM, Barkovich AJ (2001). Holoprosencephaly: new concepts. Magn Reson Imaging Clin North Am 9: 149–164. Simon EM, Hevner R, Pinter JD, et al. (2000). Assessment of the deep gray nuclei in holoprosencephaly. Am J Neuroradiol 21: 1955–1961. Simon EM, Hevner RF, Pinter JD, et al. (2001). The dorsal cyst in holoprosencephaly and the role of the thalamus in its formation.

Young ID, Madders DJ (1987). Unknown syndrome: holoprosencephaly, congenital heart defects, and polydactyly. J Med Genet 24: 714–715. Young JN, Oakes WJ, Hatten HP Jr (1992). Dorsal third ventricular cyst: an entity distinct from holoprosencephaly. J Neurosurg 77: 556–561. Handbook of Clinical Neurology, Vol. 87 (3rd series) Malformations of the Nervous System H. B. Sarnat, P. Curatolo, Editors # 2008 Elsevier B. V. 1. Introduction Septo-optic-pituitary dysplasia (SOPD) is a rare syndrome characterized by a combination of agenesis of the septum pellucidum, optic nerve hypoplasia and pituitary insufficiency.

Teratology 48: 15–19. Kovar C, Plawner L, Sweet V, et al. (2001). Cognitive profiles of children with holoprosencephaly. Arch Clin Neuropsychol 16: 781. Kundrat H (1882). Arhinencephalie als typische Art von Missbildung, Von Leuschner & Lubensky, Graz. Lee JJ, Ekker SC, von Kessler DP, et al. (1994). Autoproteolysis in hedgehog protein biogenesis. Science 266: 1528–1537. Leevers HJ, Roesler CP, Flax J, et al. (2005). The Carter Neurocognitive Assessment for children with severely 35 compromised expressive language and motor skills.

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