By Stephen R. Bakalyar (auth.), Pokar M. Kabra, Laurence J. Marton (eds.)
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Extra info for Liquid Chromatography In Clinical Analysis
For instance, rapid refilling of the pump can cause cavitation, which is the formation of gas or solvent vapor O // COMPRESSION FIG. 2. Timing diagram for a single piston pump. D "P. 2 SEC FLOW B ~c: DELIVERY J "I FIG. 3. Flow profile for a single piston pump. bubbles in the pump chamber. Currently, both Altex Division of Beckman Instruments and Varian Instrument Company offer very popular single-piston reciprocating pumps with rapid refill. A side view of the Altex 110 pump is shown in Fig. 4.
Kutt, Antiepileptic Drugs: Quantitation and Interpretation, Raven, New York, 1978. Chapter 3 Uquid Chromatography Column Technology Ronald E. Majors Varian Instrument Group Walnut Creek, Cafifornia I. Introduction The last decade has seen tremendous advances made in LC columns and column technology. tm microparticles of the 1970s, the column has not only increased the speed, resolution, and sensitivity of the technique, but has also influenced the design of instrumentation. The development of LC columns has reached a state where we are beginning at last to understand their advantages and disadvantages, their properties, their limitations, their optimum use, as well as their occasional misuse.
3. Karger, B. , Gant, J. , and Weiner, P. , J. Chromatogr. 128, 65 (1976). 4. Bakalyar, S. ,J. Chromatogr. 142, 353, (1977). 5. Giddings, J. , Dynamics of Chromatography, Part I, Dekker, New York, 1965. Chapter 2 Instrumentation for Uquid Chromatography Richard A. Henry* Scientific Systems, State College, Pennsylvania and Genrikh Sivorinovsky Altex Scientific, Berkeley, Cafifornia I. Introduction High performance liquid chromatography (HPLC) is one of the most rapidly growing and potentially largest branches of analytical chemistry.