Download Immunological Aspects of Allergy and Allergic Diseases: by K. Hajós, M.-K. Hajós (auth.), E. Rajka, S. Korossy (eds.) PDF

By K. Hajós, M.-K. Hajós (auth.), E. Rajka, S. Korossy (eds.)

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Extra info for Immunological Aspects of Allergy and Allergic Diseases: Volume 5 Clinical Aspects of Allergic Diseases

Sample text

Elucidation of the clinical picture during the 'pre-atopic period' [281] seems, however, to be very difficult. is, in our opinion, only capable of explaining the fact that various exogenous and endogenous factors may evoke asthmatic attacks in susceptible subjects [96a]. It must be emphasized, however, that sensitization of the bronchi with reagins (IgE globulins) (in experimental animals with passive transfer of reagin containing serum) is not sufficient for the production of a true asthmatic condition, even with inhalation of the adequate allergen.

G. acacia scent, the odour of stables, the odour of hairdressers' shops). The inducing factor of the asthma caused by horses may be certain air-borne substances as well as the horse dander. Fur, fragments of skin, scale, dander and feather are further inhalant allergens which may cause severe asthmatic attacks (cf. Table 50-IV). In spite of the relatively high frequency of animal dandruff allergies, comparatively few investigations have been made of the nature and origin of the allergens involved.

The equivalents of the dyscrinia are the tenacious mucus observed in the pancreas and the increased serum amylase level which has been frequently found in allergic, thus in asthmatic patients, too. Anaphylactic phenomena have often been suggested to be linked with enzyme function. Enzymes might act as antigens and at the same time preserve their specific enzyme function. g. an increased glutamic-oxalacetic transaminase level may help in differentiating an accompanying myocardial lesion, especially in the case of atypical attacks of dyspnoea.

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