By Seong-Gi Kim PhD, Peter A. Bandettini PhD (auth.), Scott H. Faro MD, Feroze B. Mohamed PhD (eds.)
Scott H. Faro and Feroze B. Mohamed have succeeded in translating benchmark examine on practical MRI into scientific purposes for the healthcare professional and cognitive neuroscientist, offering these strange with fMRI physics with a lot wanted historical past. This useful and well timed quantity offers an summary of the rules of fMRI and explains key innovations, together with scanning methodologies, experimental examine layout, and knowledge research. Informative discussions disguise the technical and scientific demanding situations linked to fMRI. A neuroanatomical atlas provides to the practical strategy and serves as an invaluable reference by means of in actual fact illustrating general functioning for vital parts of the mind. the ultimate component to the publication is dedicated to primary scientific functions of fMRI in motor, sensory, language, cognitive, and pharmacology. A concluding bankruptcy addresses destiny functions. members to this accomplished quantity contain across the world famous neuroradiologists, neurologists, psychiatrists, cognitive neuroscientists, and physicists. A wealth of four-color illustrations completes this crucial text.
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Additional info for Functional MRI: Basic Principles and Clinical Applications
Because it is the very MR signal sample located in the center of the k-space line that contributes the most to the overall image contrast, the magnetic susceptibility effects will be reﬂected in the ﬁnal image. Therefore, besides a general T2 contrast, an additional T*2 weighting is introduced into the MR signal, thus making the ASE pulse sequence more sensitive to the BOLD effect. It is possible, regardless of the echo position along the acquisition window, to cover several lines in a single iteration.
This approach allows the experimenter to obtain higher temporal resolution. Dynamic fMRI studies can be feasible using standard gradient-echo BOLD fMRI. The issues related to spatial and temporal characteristic is further discussed in detial in chapter 4 of this book. Conclusions Advancement of imaging technologies allows detections of various vascular physiological parameters induced by neural activity. Fortunately, tissue-based hemodynamic response is relatively speciﬁc to neuronal active sites.
Further on, the detection circuitry is turned on in the presence of the frequency-encoding gradient, and the MR signal is sampled along that k-space line. In the description of the spin-echo formation mechanism and the corresponding pulse sequence, it was presumed that the center of the acquisition window coincides with the center of the k-space line. h The center of the acquisition window is taken as a point of time when the phase dispersion created by the offset gradient is compensated fully by the rephasing lobe of the read-out gradient.