By Olga Krizanova, Philippe Lory, Arnold Schwartz (auth.), T. Godfraind, R. Paoletti, S. Govoni, P. M. Vanhoutte (eds.)
Although the significance of calcium (Ca2+) within the upkeep of cardiac contractility was once well-known as early as 1880, the severe position of the ion within the contractile method in skeletal, cardiac, and tender muscle has in basic terms been validated in the final 3 decades.
because the complexity of the pharmacological activities of the Ca2+ channel inhibitors grows, there's a endured have to extra make clear the inhibitors, either chemically and functionally.
This quantity presents an replace of the sector in keeping with the paintings awarded on the fifth foreign Symposium on Calcium Antagonists:Pharmacology and medical Research. It stories the present country of the turning out to be sector of molecular biology of Ca2+ channels. within the cardiovascular region, as well as the well-established scientific makes use of of Ca2+ channel inhibitors, intriguing new paintings pointing to an software in atherosclerosis is defined. The e-book additionally comprises very important makes use of of Ca2+ antagonists in novel parts of curiosity similar to the gastrointestinal tract, renal safeguard and multi-drug resistance.
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Extra info for Calcium Antagonists: Pharmacology and Clinical Research
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