By Jame Abraham, Carmen J. Allegra, James Gulley
Written by way of clinicians from the nationwide melanoma Institute and different best associations, this finished, transparent, concise oncology guide is designed in particular for speedy bedside session. It covers all malignancies and gives busy clinicians useful instructions on day-by-day sufferer administration. The hassle-free layout beneficial properties tables, charts, bullet issues, and algorithms.
The completely up-to-date moment version comprises new chemotherapeutic brokers, dosages, and remedy regimens and the most recent medical trials info. New chapters concentrate on certain remedies and complementary and replacement drugs in oncology.
The Bethesda guide of scientific Oncology, moment Edition is usually to be had for PDAs. See PDA directory for details.
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This booklet is an updated assessment of present wisdom within the box of a number of drug resistance in human melanoma. The literature as much as the center of 1993 is surveyed in professional chapters written through varied specialists. themes coated contain the molecular genetics, cytogenetics and biochemistry of the mdr genes and P-glycoprotein; substitute delivery proteins in MDR; topoisomerases I and II; cytochrome p450-enzymes and glutathione- S-transferases in MDR; mobile versions for MDR in sturdy tumours and haemopoietic tumours; immunochemical and molecular organic suggestions for detection of MDR-related gene expression; and medical and pharmacological innovations to avoid resistance.
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Extra resources for Bethesda Handbook of Clinical Oncology
The appearance of an adversarial encounter tends to be sustained by the self-fulfillment model of autonomy. This model allows little room for the complex, prioritized structure of ideals, goals, interests, desires, wishes, and whims that governs most people's lives. Everything is homogenized under the simple rubric of "values," hence any overridden value lends a false appearance of normative conflict to clinician-patient encounters. Thus, our dislike ofhospital gowns on sartorial grounds suggests a conflict of values when it is merely evidence, not of an adversarial encounter, but of value prioritization.
46 Baker Like most complex institutions, clinics are prone to intra-staff disputes. Ethicists, because oftheir relative neutrality in the territorial and hierarchical arrangements of clinical institutions, and because of their identification with the idea of ethics, are often appealed to (as neutrals) to arbitrate any number of disputes, many of which are only remotely ethical in nature. Although arbitration is not a major role for most clinical ethicists, itis worth mentioning because it underlines the close association between the idea of ethics and the person of the clinical ethicist, at least in the mind of clinicians.
Who, then, has the most to gain by having an external, relatively neutral party review clinician and patient interpretations of a situation? The patient would seem to have little to lose and everything to gain from the presence of a neutral party who can activate moral concern on the part ofthe more powerful, vertical clinician. , even the ethicist who functioned merely as a redundant echo of clinical values, would still serve the patient's interests well. For merely by being a presence in the clinical complex, the ethicist inspires a concern for, and a discussion of, moral issues that are often ignored-typically to the patient's detriment.