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By J. Esparza-Gordillo

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These lines of evidence suggested a new model system for antigen-induced dermatitis. , 2009). , 2011). 3 Establishment of hairless NC mice for the development of drugs and comprehensive therapy for human AD Although the NC model is a promising mouse model for AD, it has another serious drawback, namely the existence of dense hair on the body. The dense hair disturbs the pathological observation of the symptoms in the earlier stages of AD onset and without hair shaving also interferes with the painting of an ointment to test its efficacy.

2009) Oral administration of Yokukansan inhibits the development of atopic dermatitis-like lesions in isolated NC/Nga mice. Journal of Dermatological Science, Vol. 56, No. W. & Lee do, I. (2009) Therapeutic advantages of medicinal herbs fermented with Lactobacillus plantarum, in topical application and its activities on atopic dermatitis. Phytotherapy Research, Vol. 23, No. , Shin, T. & Matsuda, H. (2011). Peroxisome proliferator-activated receptor gamma-mediated suppression of dendritic cell function prevents the onset of atopic dermatitis in NC/Tnd mice.

6, (December 2003), pp. M. (1982). Atopic dermatitis. 1, (January 1982), pp. M. & Rajka, G. (1980). Diagnostic features of atopic dermatitis. 92, pp. , Tanaka, H. & Maru M. (1997). Naturally occurring dermatitis associated with Staphylococcus aureus in DS-Nh mice. 3, (July 1997), pp. , Ichihashi, M. & Horikawa T. (2002). Characterization of dermatitis arising spontaneously in DS-Nh mice maintained under conventional conditions: another possible model for atopic dermatitis. , Deleuran, M. & Vestergaard, C.

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